Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5167884 | Phytochemistry | 2006 | 7 Pages |
Abstract
Bioassay-directed fractionation of the CHCl3 extract of the dried stems of Rourea minor (Gaertn.) Aubl. (Connaraceae) liana led to the isolation of two glycosides, rourinoside (1) and rouremin (2), as well as five known compounds. Compounds 1-3 showed weak in vitro activities against Plasmodium falciparum. Their structures and stereochemistry were elucidated by spectroscopic methods and selected enzyme hydrolysis.
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Authors
Zhen-Dan He, Cui-Ying Ma, Ghee Teng Tan, Kongmany Sydara, Pamela Tamez, Bounhoong Southavong, Somsanith Bouamanivong, D. Doel Soejarto, John M. Pezzuto, Harry H.S. Fong, Hong-Jie Zhang,