| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5167905 | Phytochemistry | 2006 | 10 Pages |
Abstract
Several types of isoquinoline alkaloids were tested for their inhibitory activities against Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoyl-phorbol-13-acetate in Raji cells. In addition, these alkaloids were evaluated with respect to their ability to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals. The results suggest that some of these isoquinoline alkaloids might be valuable as potential cancer chemopreventive agents. For both tests, structure-activity relationships are discussed.
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Physical Sciences and Engineering
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Organic Chemistry
Authors
Wenhua Cui, Kinuko Iwasa, Harukuni Tokuda, Akiko Kashihara, Yosuke Mitani, Tomoko Hasegawa, Yumi Nishiyama, Masataka Moriyasu, Hoyoku Nishino, Miyoji Hanaoka, Chisato Mukai, Kazuyoshi Takeda,