Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5173580 | Phytochemistry | 2013 | 5 Pages |
Abstract
The major alkaloids of the aerial parts of a Turkish sample of Papaver pseudo-orientale are salutaridine and a new alkaloid, macrantaline, UV, IR, PMR, MS and CD have been used to establish the structure of macrantaline as 1-(2â²-hydroxymethylene-3â²,4â²-dimethoxybenzyl)-2-methyl-6,7-methylenedioxy-8-methoxy-1,2,3,4-tetrahydroisoquinoline. The corresponding 2â²-methyl substituted analogue prepared from (â)-α-narcotine and also from macrantaline proved to have identical properties, including CD spectra, thus confirming the structure and establishing the absolute configuration of macrantaline. A new minor alkaloid, macrantoridine, yielded macrantaline on lithium aluminium hydride reduction and differs from the latter in that the 2â²-substituent is a carboxyl instead of hydroxymethylene. UV, IR, PMR, MS and CD data are reported for macrantoridine.
Related Topics
Physical Sciences and Engineering
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Authors
Günay Sariyar, J.David Phillipson,