| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5176156 | Phytochemistry Letters | 2015 | 6 Pages |
Abstract
Activity-guided isolation of the Azadirachta excelsa MeOH extract using TOP assay led to the isolation of one new (1) and seven known (2-8) limonoids. Compound 4 exhibited TCF/β-catenin transcription inhibitory activity. It showed selective cytotoxicity against HCT116 and AGS which have active Wnt signal.
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Authors
Rolly G. Fuentes, Kazufumi Toume, Midori A. Arai, Samir K. Sadhu, Firoj Ahmed, Masami Ishibashi,