Article ID Journal Published Year Pages File Type
5176606 Phytochemistry Letters 2014 5 Pages PDF
Abstract

- Horizontoates A-C were isolated from Cotoneaster horizontalis Decne.
- The structures of these compounds were elucidated by chemical and modern spectroscopic techniques.
- Compounds 1 and 2 showed significant inhibitory effects on acetylcholinesterase (AChE) and butylcholinesterase (BChE) in a dose-dependent manner.
- The IC50 values of compounds 1-2 were 1.54 and 3.41 μM against AChE while 5.97 and 6.84 μM against BChE, respectively.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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