| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5176680 | Phytochemistry Letters | 2015 | 6 Pages |
Abstract
The biotransformation of cyclopamine (1) and its congeners (2, 3 and 4) by Cunninghamella echinulata (ACCC 30369) was investigated. The chemical structures of two new congeners (2 and 4) and nine new metabolites were elucidated by NMR, HRESIMS and X-ray diffraction studies. Moreover, the relevant biological activities and the acid stabilities were also reported.
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Authors
Qing-xin Liu, Xing Yuan, Ji Ye, Rong-cai Yue, Yun-heng Shen, Lei Shan, Hui-liang Li, Wei-dong Zhang,