| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5176713 | Phytochemistry Letters | 2011 | 4 Pages |
Abstract
⺠From Indonesian medicinal plant Lunasia amara, two new acridone alkaloids, 5-hydroxygraveroline (1) and 8-methoxyifflaiamine (2), were isolated together with 12 known ones. Among the 14 compounds isolated, 5-hydoroxygraveoline (1) and lunamarine (3) showed moderate inhibition selective to CYP2D6 with IC50 values of 4.7 and 1.8 μM, respectively.
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Authors
Subehan Subehan, Naoto Takahashi, Shigetoshi Kadota, Yasuhiro Tezuka,