| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5176963 | Phytochemistry Letters | 2013 | 5 Pages |
Abstract
- Microbial transformation of β-lapachone furnished two new glycosylated derivatives.
- These metabolites are similar to those that occur in phase II of human metabolism.
- The major derivative was less active and more selective than β-lapachone.
- The results are valuable for the development of rational approaches in drug design.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Camila R. Paludo, Eduardo A. da Silva-Junior, Raquel A. Santos, Mônica T. Pupo, Flávio S. Emery, Niege A.J.C. Furtado,