| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5177094 | Phytochemistry Letters | 2011 | 4 Pages |
Abstract
The cytotoxic Laurencia metabolite thyrsiferol (1) is a structurally unique mitochondrial complex I inhibitor (IC50 3 μM) that inhibits hypoxia-induced HIF-1 activation in T47D human breast tumor cells.
Keywords
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Organic Chemistry
Authors
Fakhri Mahdi, Miriam Falkenberg, Efstathia Ioannou, Vassilios Roussis, Yu-Dong Zhou, Dale G. Nagle,