| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5177170 | Phytochemistry Letters | 2009 | 4 Pages |
Abstract
The new antiplasmodial flavonoid 3-methoxy carpachromene was identified in an extract of Pistacia atlantica by HPLC-based activity profiling. After isolation, assignment of the 1H and 13C NMR resonances was carried out by extensive analysis of its NMR spectra and the spectra of its diacetate derivative. 3-Methoxy carpachromene had an IC50 of 3.4 μM (1.25 μg/ml) against Plasmodium falciparum K1.
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Authors
Michael Adams, Inken Plitzko, Marcel Kaiser, Reto Brun, Matthias Hamburger,