Eremophilane and eudesmane sesquiterpenoids and a pimarane diterpenoid from the wood-decay fungus Xylaria sp. BCC 5484

Three new sesquiterpenoids (1-3) and a new pimarane-type diterpenoid (4) were isolated from the fermentation broth of the wood-decay fungus Xylaria sp. BCC 5484. The structures were elucidated by analyses of NMR spectroscopic and mass spectrometry data. The absolute configuration of eremophilane 1 was addressed by application of the modified Mosher's method.

Graphical abstractThree new sesquiterpenoids (1-3) and a new pimarane-type diterpenoid (4) were isolated from the fermentation broth of the wood-decay fungus Xylaria sp. BCC 5484.Download full-size imageHighlights► Three new sesquiterpenes and a new diterpene were isolated from cultures of the wood-decay fungus Xylaria sp. BCC 5484. ► The structures were elucidated on the basis of spectroscopic data. ► The absolute configuration of the new eremophilane (1) was determined by application of the modified Mosher's method.