| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5177294 | Phytochemistry Letters | 2009 | 5 Pages |
Abstract
The leaves of Brassaiopsis glomerulata (Araliaceae), collected in Indonesia, were found to inhibit aromatase, the rate-limiting enzyme in the production of estrogens from androgens, in both enzyme- and cell-based aromatase inhibition assays. Bioassay-guided fractionation led to the isolation of 13 compounds, including the new natural product, N-benzoyl-l-phenylalanine methyl ester.
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Authors
Marcy J. Balunas, Bin Su, Soedarsono Riswan, Harry H.S. Fong, Robert W. Brueggemeier, John M. Pezzuto, A. Douglas Kinghorn,