| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5177320 | Phytochemistry Letters | 2011 | 6 Pages |
Abstract
⺠The methanol extract, furanocoumarin fraction and the major coumarins of the fruits of Angelica officinalis L. were tested against cholinesterase enzyme inhibitory and antioxidant activity. ⺠Imperatorin, xanthototixn, and bergapten showed a higher and selective inhibition against BChE. ⺠The samples showed antioxidant activity from ignorable to moderate level. ⺠Molecular docking simulations of the tested coumarins into BChE confirmed the strong interactions between them.
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Authors
Fatma Sezer Senol, Krystyna Skalicka Woźniak, Mahmud Tareq Hassan Khan, Ilkay Erdogan Orhan, Bilge Sener, Kazimierz GÅowniak,