Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5177355 | Phytochemistry Letters | 2012 | 4 Pages |
Two new anthraquinone glycosides Strepnoneside A (1) and Strepnoneside B (2), together with Chromomycin A3 (3), were isolated from cultures of the marine Streptomyces sp. strain. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. Compound 3 exhibited cytotoxic activities against HCT 116 cell lines (IC50 = 300 ± 11 pM).
Graphical abstractTwo new anthraquinone glycosides, together with Chromomycin A3, were isolated from cultures of the marine Streptomyces sp. strain. Their structures were determined by spectroscopic methods.Download full-size imageHighlights⺠Two anthraquinone glycosides and Chromomycin A3 were isolated from marine Streptomyces sp. strain. ⺠The structures of the new compounds were determined by detailed analysis of spectral data. ⺠Compound 3 exhibited cytotoxic activities against HCT 116 cell lines.