Spicachlorantins A and B, new dimeric sesquiterpenes from the roots of Chloranthus spicatus

Two new lindenane sesquiterpene dimers, spicachlorantins A and B (1 and 2), were isolated from the roots of Chloranthus spicatus along with a known related compound, chloramultilide A (3). Their structures and the absolute stereostructures were established by 1D and 2D NMR as well as by CD spectroscopic analyses.

Graphical abstractTwo new (1 and 2) and a known (3) lindenane-type dimeric sesquiterpenes, possessing an 18-membered trilactone-ring composed of a 4-hydroxy-2-methylbut-2-enoyl group and a succinyl group, were isolated from the roots of Chloranthus spicatus, which is used as traditional medicine by ethnic minority groups in China. The structures were determined by extensive spectroscopic examinations.Download full-size image