| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5177531 | Phytochemistry Letters | 2008 | 4 Pages |
Abstract
Eleven derivatives of amentoflavone and hinokiflavone from the Indian herb Selaginella bryopteris have been investigated for antiprotozoal activity using in vitro assays against Plasmodium falciparum, Leishmania donovani and Trypanosoma spp. Highest antiprotozoal activity was displayed by 7,4â²,7â³-tri-O-methylamentoflavone against the K1 strain with an IC50 of 0.26 μM and a cytotoxicity evaluated using L-6 cells of >160 μM, respectively.
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Authors
Olaf Kunert, Rumalla C. Swamy, Marcel Kaiser, Armin Presser, Silke Buzzi, A.V.N. Appa Rao, Wolfgang Schühly,