Article ID Journal Published Year Pages File Type
5177534 Phytochemistry Letters 2008 5 Pages PDF
Abstract
The new triterpene saponin, β-d-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (1) together with the known combregenin (2), arjungenin (3), arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle. Their structures were identified by interpretation of their spectral data, mainly ESIMS, 1D NMR (1H, 13C NMR, DEPT) and 2D NMR (COSY, HSQC and HMBC), and by comparison with the literature. Compounds 1-3 exhibited more significant anti-inflammatory activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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