| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5177551 | Phytochemistry Letters | 2008 | 4 Pages |
The ethyl acetate extract of the aerial parts of Ajuga turkestanica afforded 6 neo-clerodane diterpenes, including two novel compounds, 14,15-dihydroajugachin B (1) and 14-hydro-15-methoxyajugachin B (2), in addition to the known diterpenoids chamaepitin (3), ajugachin B (4), ajugapitin (5) and lupulin A (6). Structures were established through exhaustive NMR spectroscopic analysis and chemical transformation in the case of 1. The full 1H and 13C NMR assignment of the C-15 R and S configurations of 14-hydro-15-methoxyajugachin B and chamaepitin were elucidated.
Graphical abstractThe ethyl acetate extract of Ajuga turkestanica afforded 6 neo-clerodane diterpenes, including two novel compounds: 14,15-dihydroajugachin B (1) and 14-hydro-15-methoxyajugachin B (2), in addition to the known diterpenoids chamaepitin, ajugachin B, ajugapitin and lupulin A.
