Article ID Journal Published Year Pages File Type
5177553 Phytochemistry Letters 2008 5 Pages PDF
Abstract
24(R)-Ethylcholest-6-ene-5α-ol-3-O-β-d-glucopyranoside (1), along with 11 known compounds (2-12) including aporphine alkaloids, diterpenes, a steroid glycoside and a flavonoid glycoside were isolated from the leaves of Nelumbo nucifera and evaluated for their antifungal, antimalarial and for cytotoxic activities. Antifungal activity was observed for (R)-roemerine (3) and antimalarial activity for (R)-roemerine (3) and N-methylasimilobine (5). Position C-1 and C-2 of aporphine alkaloids is crucial for antimalarial activity.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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