New spermidine alkaloids from Capparis spinosa roots

Capparis spinosa L. (Capparidaceae) is a medical plant widely distributed in Xinjiang Uighur Autonomous Region, China. It has been used since ancient times in traditional medicine especially for the treatment of rheumatism and gout. In an earlier research, we have isolated and identified the alkaloids from C. spinosa fruits. As a part of ongoing research, we have investigated the roots of C. spinosa. The present paper reports the isolation and characterization of three novel spermidine alkaloids. Three new alkaloids capparispine (1), capparispine 26-O-β-d-glucoside (2) and cadabicine 26-O-β-d-glucoside hydrochloride (3) were isolated from the roots of C. spinosa.