Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5182467 | Polymer | 2012 | 5 Pages |
Abstract
A novel conjugated cationic polyfluorene containing aminated tetraphenylethene (ATPE) unit is developed as a sensitive and selective fluorescence probe for heparin detection based on the combination of aggregation-induced emissive property of the ATPE units and the FRET process from the blue-emissive polyfluorene segments to the yellow-emissive ATPE units. The addition of anionic heparin will lead to the formation of heparin/polymer complexes, and turn on the aggregation-induced yellow emission of the ATPE units. A good linear relationship is found between the yellow emission intensity of the ATPE units and the heparin concentrations with a limit of detection of 30Â nM in aqueous buffer.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bowei Xu, Xiaofu Wu, Haibo Li, Hui Tong, Lixiang Wang,