| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5185439 | Polymer | 2010 | 8 Pages |
Abstract
Novel three-dimensional (3-D) nano-/microfibrous poly(lactic-co-glycolic acid) (PLGA) scaffolds were fabricated by hybrid electrospinning, involving a combination of solution electrospinning and melt electrospinning. The scaffolds consisted of a randomly oriented structure of PLGA microfibers and PLGA nanofibers. The cell attachment and spreading of normal human epidermal keratinocytes (NHEK) and fibroblasts (NHEF) were several times higher in the PLGA nano-/microfiber composite scaffolds than in the microfibrous scaffolds without nanofibers. This shows that the presence of nanofibers enhanced the attachment and spreading of the cells on the nano-/microfiber composite scaffolds.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sung Jin Kim, Da Hyun Jang, Won Ho Park, Byung-Moo Min,