Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5186485 | Polymer | 2006 | 4 Pages |
Abstract
A one-step way to prepare organosilica@chitosan crosslinked nanospheres was developed through self-assembly of amphiphilic copolymers synthesized by concurrent grafting polymerization and sol-gel reaction. The core 'organosilica' was formed by hydrolysis and condensation of an alkyloxosilane-3-(trimethoxysilyl) propyl methacrylate (TMSPM) that was simultaneously polymerized using chitosan/tert-butyl hydroperoxide (TBHP) as redox-pair initiator. The well-defined nanospheres had adjustable sizes below 100Â nm, and had not harmful residues impeding medical applications. This synthesis method simplified the preparation of silica@polymer spheres by eliminating the previous core-forming step, and could apply many water-soluble biopolymers containing -NH2 groups as the shell materials.
Related Topics
Physical Sciences and Engineering
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Authors
Bin Fei, Haifeng Lu, John H. Xin,