| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5202901 | Polymer Degradation and Stability | 2011 | 6 Pages |
Abstract
A poly(lactic acid) (PLA)-like terpolyester consisting of 96 mol% lactate (LA), 1 mol% 3-hydroxybutyrate and 3 mol% 3-hydroxyvalerate was produced in recombinant Escherichia coli LS5218 expressing LA-polymerizing enzyme (LPE). The strain was grown on glucose with a feeding of valerate as the monomer precursor. The glass transition and melting temperatures of the terpolyester were close to those of chemically synthesized poly(L-LA)s (PLLAs) having similar molecular weights. Additionally, a blend of the terpolyester, which was composed entirely of (R)-LA (D-LA) due to the strict enantiospecificity of LPE, with PLLA formed a stereocomplex with higher melting temperature (201.9 °C). These results indicate that the biological PLA-like polyester produced via this one-step microbial process has comparable thermal properties to chemically synthesized PLAs.
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Authors
Fumi Shozui, Ken'ichiro Matsumoto, Ren Motohashi, Jian Sun, Toshifumi Satoh, Toyoji Kakuchi, Seiichi Taguchi,