Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5206688 | Polymer Testing | 2012 | 8 Pages |
Abstract
Chitosan fiber mats were successfully processed by electrospinning. The as-spun fiber mats were neutralized with ethanol and cross-linked with glutaraldehyde. A decrease of the fiber average diameter from 243 ± 43 nm down to 215.53 nm was observed for the neutralized and cross-linking chitosan membrane. It was found that the processing conditions do not alter the initial deacetylation degree of the polymer.Polymer crystallinity index showed a decrease from 61% for the Protasan material down to 17% for the cross-linking fiber mats. A swelling index up to 1000% was observed for the cross-linked samples. Preliminary MC-3T3-E1cell culture results showed good cell adhesion and proliferation in the cross-linked chitosan fiber mats.
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Authors
V. Sencadas, D.M. Correia, C. Ribeiro, S. Moreira, G. Botelho, J.L. Gómez Ribelles, S. Lanceros-Mendez,