Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5208254 | Progress in Polymer Science | 2013 | 25 Pages |
Abstract
Tissue engineering approach focuses on the regeneration of deficient or damaged tissues of the body. Regeneration of dental tissues is considered as a promising therapeutic approach in dental tissue engineering. Engineering the environment for developing tissues comprises of biomaterials, growth factors, stem cells and regulation of physiological conditions in a spatial and temporal manner. To enhance the structural stability and bioactivity of polymers, a wide variety of nanomaterials are being utilized in dental regenerative medicine. Nanostructured biopolymers in the form of scaffolds, hydrogels, nanofibers, dendrimers, films, etc. and nanostructured bioceramics such as hydroxyapatite, bioactive glass ceramic/bioglass, etc. in the form of nanoparticles, nanocrystals, nanorods, paste, etc. are being exploited in the simultaneous regeneration of hard and soft tissues of the human body. In the dental area, these different forms closely mimic the natural constituents and framework of the dental tissues, namely enamel, dentin and periodontium. Overall this review essentially focuses on the role of polymeric and ceramic nanomaterials in the area of dental tissue engineering, highlighting their specific applications in enamel, dentin and periodontal regeneration.
Keywords
ECMPVACPCEGFRPLGADEXPCLEDSEMDHRTEMBCPPDLCPLAEMACaCO3RGDPPITricalcium phosphateRUNX2SBFFAKRT-PCRERKFFTGBRNa2HPO4BSPNAGhUCMSCsSD ratOPNPLLPLLASDF-1αEoEOCNhBMSCsBMP-7PDLGTRBGCMG-63SCAPLcstDPSCrhBMP2DFCsPLCLPolypropylenimineMetronidazole benzoateOFDCeramicsALPAlkaline phosphataseAktEthyl methacrylateHuman primary osteoblastsOsteopontinOsteocalcinHyaluronic acidGuided tissue regenerationGuided bone regenerationBrdUbromodeoxyuridinePolymersFourier transformScaffoldsLower critical solution temperatureSHEDDexamethasonePeriodontal ligamentHEAPeriodontal ligament cellHuman osteosarcoma cellsHuman bone marrow stromal cellsStem cells from human exfoliated deciduous teethstem cells from apical papillaDental pulp stem cellsbone sialoproteinCalcium phosphate cementextracellular signal regulated kinasesFTIRFourier transform infrared spectroscopyenergy dispersive spectroscopyDentinRunt-related transcription factor 2Biphasic calcium phosphateTCPextra cellular matrixEnamel matrix derivativeSimulated body fluidSEMMETSprague Dawley ratEnamelscanning electron microscopehigh resolution transmission electron microscopeNanofibersNanomaterialsNanosilverHydroxyapatiteHydroxyethyl methacrylatepolymerase chain reactionreverse transcription polymerase chain reactionPCRPAMAMXRDX-ray diffractionBone morphogenetic protein-7Serine/threonine protein kinasePoly(L-lactic acid)poly(lactic-co-glycolic acid)PolyamidoaminePolylactic acidPoly(vinyl alcohol)PolycaprolactonePoly-l-lysinePeptide amphiphileCalcium carbonateCaPfocal adhesion kinaseHAp
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
S. Sowmya, Joel D. Bumgardener, Krishna Prasad Chennazhi, Shantikumar V. Nair, R. Jayakumar,