| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5208441 | Progress in Polymer Science | 2013 | 17 Pages |
Abstract
This review summarizes the major synthesis pathways that are employed in the preparation of this type of polymer therapeutics and the polymer structural key factors that are of relevance to enhanced therapeutic efficacy. Herein, new synthesis approaches, based on “controlled”/living radical polymerization techniques, are highlighted.
Keywords
CLRPFDALDL-CATRPBAsBile acid sequestrantsUltravioletAtom transfer radical polymerizationReversible addition-fragmentation chain transferTemPolymerscardiovascular diseaseGastrointestinalCVDRAFTFood and Drug AdministrationFRPlow density lipoproteinLDLSEMScanning electron microscopyTransmission electron microscopyFree radical polymerizationLiving radical polymerizationDrug discoverycholesterollow density lipoprotein cholesterol
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
PatrÃcia V. Mendonça, Arménio C. Serra, Cláudia L. Silva, Sérgio Simões, Jorge F.J. Coelho,