| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5210284 | Reactive and Functional Polymers | 2013 | 4 Pages |
Abstract
A polystyrene-supported vinyl sulfone reagent was prepared and used for the solid-phase organic synthesis of 1-monosubstituted 1,2,3-triazoles via a 1,3-dipolar cycloaddition reaction with azides and subsequent cleavage from the polymer support through an elimination reaction in the presence of potassium tert-butoxide. The advantages of this method include straightforward operation, good yield and high purity of the crude products.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhenzhong Huang, Ruiling Wang, Shouri Sheng, Ruyi Zhou, Mingzhong Cai,