Article ID Journal Published Year Pages File Type
5211619 Reactive and Functional Polymers 2006 7 Pages PDF
Abstract
A general method for the liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described. The poly (ethylene glycol) (PEG)-supported acrylate (2) or methyl acrylate (6) reacted with nitrile oxides generated in situ from aldoximes 3, followed by cleavage from the PEG, to give isoxazolines in good yield and purity.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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