Article ID Journal Published Year Pages File Type
5211869 Tetrahedron 2017 8 Pages PDF
Abstract

Thioethers are of synthetic value in pharmaceutical molecules and nature products, herein, we report an oxidative cascade reaction that delivers multiple substituted indole thioethers with great efficiency. This transformation utilized ortho-azido aromatic alkynes as the substrates, and sulfonyl hydrazides as the sulfenation reagent promoted by Mn(III) catalyst. Notably, great functional group tolerance, in combination with nitrogen and water as the byproducts, highlighted the sustainable chemistry of this protocol.

Graphical abstractDownload high-res image (103KB)Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, ,