Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5211869 | Tetrahedron | 2017 | 8 Pages |
Abstract
Thioethers are of synthetic value in pharmaceutical molecules and nature products, herein, we report an oxidative cascade reaction that delivers multiple substituted indole thioethers with great efficiency. This transformation utilized ortho-azido aromatic alkynes as the substrates, and sulfonyl hydrazides as the sulfenation reagent promoted by Mn(III) catalyst. Notably, great functional group tolerance, in combination with nitrogen and water as the byproducts, highlighted the sustainable chemistry of this protocol.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lin He, Xianwei Li,