| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5211987 | Tetrahedron | 2017 | 9 Pages |
Abstract
A simple and efficient two step synthesis of coumestans is described. The key reaction in the synthesis is the use of easily available Cu(OAc)2 for CH functionalization of 3-(2-hydroxyphenyl)coumarin to give coumestan ring system via formal oxidative cyclization. This approach provided a short protective group free route to naturally occurring coumestrol and 4â²-O-methylcoumestrol.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mayuri M. Naik, Vijayendra P. Kamat, Santosh G. Tilve,