| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5212127 | Tetrahedron | 2017 | 7 Pages |
Abstract
Enantioselective synthesis of crotyl geminal bis(silane) 4 has been developed by an asymmetric [1, 5]-hydride shift of allylic hydrazine. SnCl4-promoted Sakurai allylation of (R)-4 with acetals leads to chemoselective desilylation of SiMe3, generating E-syn-(S, R)-5 in good yields with high E/Z-, diastereo- and enantioselectivity.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yang Chu, Qiang Pu, Zhixing Tang, Lu Gao, Zhenlei Song,