| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5212351 | Tetrahedron | 2017 | 8 Pages |
Abstract
The iron(II) chloride- and copper(I) iodide-mediated carbozincation of a panel of substituted ynamides is described in this article. The reaction is totally regio- and stereoselective. Experiments showed that the reaction mediated with Fe(II) was more substrate dependent than the reaction performed with Cu(I). Interestingly, in the presence of allylbromide, stereoselective carboallylation can be achieved for the first time in a one-pot procedure, leading to skipped dienamides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hugo Lingua, François Vibert, Dominique Mouysset, Didier Siri, Michèle P. Bertrand, Laurence Feray,