| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5212452 | Tetrahedron | 2017 | 8 Pages |
Abstract
An efficient asymmetric Michael reaction of 1,3-dicarbonyl compounds with α-Substituted-β-Nitroacrylates has been developed by using a cinchona-thiourea bifunctional organocatalyst in high yields and enantioselectivies. One of adducts could be transformed into a chiral β-nitroester bearing an isoxazole skeleton and an all-carbon quaternary chiral center.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hsuan-Hao Chang, Kai-Ti Chu, Ming-Hsi Chiang, Jeng-Liang Han,