Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5212487 | Tetrahedron | 2017 | 18 Pages |
Abstract
From what began as a casual discovery of the ketene-Claisen rearrangement (the Malherbe-Belluš rearrangement) over 3 decades ago has flourished a reaction of substantial significance. The noticeable qualities of the ketene-Claisen rearrangement is accomplished in terms of experimental simplicity, forming new CC bonds, high levels of chemo- and stereocontrol, ring enlargements and constructing new stereocenters. This survey of the ketene-Claisen rearrangement with some applications in organic synthesis will not only recapitulate the prospective of this reaction so far but also illustrate the achievable future significant prospective.
Graphical abstractDownload high-res image (153KB)Download full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Adeem Mahmood,