| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5212825 | Tetrahedron | 2017 | 9 Pages |
Abstract
A one-pot multi-component synthesis of indenone-fused heterocyclic derivatives from readily available starting materials including diamines, 1,1-bis(methylthio)-2-nitroethene, 1,3-indandione and aromatic aldehydes in excellent yields is described. The sequence of cascade reactions include Knoevenagel condensation, enamine formation, Michael addition, imine-enamine tautomerization and cyclization. The diastereoselective synthesis of cis-indenohydropyridine have been definitively proven by X-ray crystallography.
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