Article ID Journal Published Year Pages File Type
5212864 Tetrahedron 2016 10 Pages PDF
Abstract

A one-pot synthesis of 1,2-disubstituted 2-imidazolines from N-(2-haloethyl)amides has been developed. The reaction affords high yields of diverse 1,2-disubstituted 2-imidazolines from triflic anhydride-mediated dehydration of amides followed by installation of a primary amine.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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One-pot triflic anhydride-mediated synthesis of 1,2-disubstituted 2-imidazolines from N-(2-haloethyl)amides and amines
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