| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5212884 | Tetrahedron | 2016 | 8 Pages |
Abstract
The chemical reactivities of four catecholamines, N-acetyl dopamine (NADA) and its dehydro derivative (NAÎDA), N-acetyl 3,4-dihydroxy-phenylalanine methyl ester (NADOPAME) and its dehydro derivative (NAÎDOPAME), under oxidative nucleophilic trapping and polymerisation conditions were compared and contrasted. Despite their structural similarities, varying reactivities and regioselectivities for oxidative nucleophilic trapping with ethanethiol were observed. This has possible implications on the use of these natural building blocks and their derivatives in the design and synthesis of biomimetic materials.
Graphical abstractDownload high-res image (273KB)Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yong Shung Cheah, Sridhar Santhanakrishnan, Michael B. Sullivan, Koon Gee Neoh, Christina L.L. Chai,