| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5212984 | Tetrahedron | 2016 | 6 Pages |
Abstract
The formal dipolar behaviour of furan-2,3-diones is illustrated by their reaction with ethyl glyoxylate under Lewis basic activation uniquely, giving access to isotetronic derivatives. The Janus-type nature of the activated species, both nucleophilic and electrophilic is revealed by ring-opening of the starting ketolactone. An unexpected reversible side-reaction was identified by in situ monitoring.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vincent Barbier, François Couty, Olivier R.P. David,