| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213167 | Tetrahedron | 2016 | 8 Pages |
Abstract
The use of Direct Imine Acylation (DIA) methodology for the total synthesis of pallimamine is described, with three different synthetic routes examined. The construction of three advanced δ-lactam precursors, all utilising DIA, is described, along with attempts to progress these compounds further, using three distinct desymmetrisation strategies, two involving alcohol-aryl coupling, and a third involving an unusual diastereoselective lactonisation.
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