Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5213188 | Tetrahedron | 2016 | 5 Pages |
Abstract
The palladium-catalyzed three-component cycloaminocarbonylation of 2-formylaryl tosylates with hydrazines and carbon monoxide has been established, which provides an efficient method for synthesis of substituted phthalazinones. In addition, by applying this protocol as the key step, Hydralazine can easily be synthesized in 65% yield.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bin Liu, Chunlei Zhang, Xigeng Zhou,