| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213280 | Tetrahedron | 2016 | 5 Pages |
Abstract
We present an efficient synthesis of α-azido-β-dicarbonyl compounds from β-dicarbonyl compounds and trimethylsilyl azide, catalyzed by guanidinium hypoiodite. The reaction can be run in air at ambient temperature (up to 40 °C) and is not sensitive to moisture. The substrate scope is broad, including cyclic and linear β-dicarbonyl compounds, and the α-azide products are obtained in 55%-99% yield.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Koji Yasui, Kohei Kojima, Takanari Kato, Minami Odagi, Masaru Kato, Kazuo Nagasawa,