| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213328 | Tetrahedron | 2016 | 9 Pages |
Abstract
We report herein a transition-metal-free coupling reaction of arylboronic acids with benzyl halides and mesylates for the construction of C(sp2)C(sp3) bonds. A unique feature of this coupling reaction is the formation regioisomers in some cases. Mechanistic studies suggest that this reaction may proceed via an unprecedented Friedel-Crafts-type reaction pathway under base conditions with the assistance of boronic acid moiety.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Guojiao Wu, Shuai Xu, Yifan Deng, Chaoqiang Wu, Xia Zhao, Wenzhi Ji, Yan Zhang, Jianbo Wang,