Achievement of regioselectivity in transition metal-catalyzed direct C-H (hetero)arylation reactions of heteroarenes with one heteroatom through the use of removable protecting/blocking substituents or traceless directing groups

Article ID	Journal	Published Year	Pages	File Type
5213498	Tetrahedron	2016	62 Pages	PDF

Keywords

BOC DBU TBAF 4-dimethylaminopyridine n-butyl TFA Cyclohexyl n-Bu AcAc tert-butoxycarbonyl 2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl NMP DMF AIBN n-Hex Cyclopentadienyl Azobisisobutyronitrile TBAB N-methyl-2-pyrrolidone 1-Adamantyl dppb Xphos t-butyl triisopropylsilyl THF DMA i-Pr DMAP DCE trifluoromethanesulfonyl (2,2,6,6-tetramethylpiperidin-1-yl)oxyl 1,2-dichloroethane 1,4-bis(diphenylphosphino)butane 1,4-benzoquinone DFT DMSO N,N-Dimethylacetamide N,N-dimethylformamide Trifluoroacetate aryl ethyl Deprotection Acetyl acetylacetonate Tetrahydrofuran LDA t-Bu Room temperature Dimethylsulfoxide Regioselectivity TEMPO Chemoselectivity Molecular sieves Lithium diisopropylamide Methyl SEM Density functional theory TIPS Pyridine Transition metal catalysts

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Achievement of regioselectivity in transition metal-catalyzed direct C-H (hetero)arylation reactions of heteroarenes with one heteroatom through the use of removable protecting/blocking substituents or traceless directing groups

Authors

Renzo Rossi, Marco Lessi, Chiara Manzini, Giulia Marianetti, Fabio Bellina,