| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213617 | Tetrahedron | 2016 | 14 Pages |
Abstract
γ-Carbolines were prepared from pyrido[4,3-b]-5H-indoles via Pd(0)-catalysed, stereo and regioselective allene/uridine allene insertion 3- and 5-component cascades. This versatile reaction sequence gives a range of structurally diverse carboline derivatives and tolerates a broad range of substrates. The power of this approach has been harnessed to produce γ-carboline based HDAC inhibitors.
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