New fluorescent probe based on rhodamine derivative for detection of both Cu2+ and L-Methionine and living cells imaging

This paper developed a new fluorescent rhodamine-based derivatives (RAD) probe for highly sensitive and selective detection of Cu2+ and L-Methionine (L-Met). The detection limits can reach as low as 12 nM for Cu2+ and 5 nM for L-Met, In addition, the RAD probe can be further applied to cell imaging owing to its photostability and low cytotoxicity.

Graphical abstractA new fluorescent rhodamine-based derivatives (RAD) probe for highly sensitive and selective detection of Cu2+ and L-Methionine (L-Met) was developed with the detection limits can reach as low as 12 nM for Cu2+ and 5 nM for L-Met, In addition, the RAD probe can be further applied to cell imaging owing to its photostability and low cytotoxicity.Download high-res image (196KB)Download full-size image