| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213664 | Tetrahedron | 2016 | 6 Pages |
Abstract
Functionalized tetrahydrofluorenes were synthesized using a normal electron-demand Diels-Alder cycloaddition reaction between 2-vinylindenes and various dienophiles. Electron rich 2-vinylindenes bearing methoxy groups at the 4- and 7- positions were accessed through their corresponding 2-indenylpivalates obtained using a Pt-catalyzed cycloisomerization reaction. DFT calculations were used to rationalize the observed regioselectivity in the Diels-Alder reaction, and the cycloadditions were extended to a 2-allenylindene substrate.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sidney M. Wilkerson-Hill, Christián M. Lavados, Richmond Sarpong,