| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213819 | Tetrahedron | 2016 | 9 Pages |
Abstract
A method for acylation for heteroarenes under metal-free conditions has been described using NCS as an additive and TBHP as an oxidant. This method has been successfully employed in acylation of a variety of aldehyde with heteroarenes. The application of the method has been illustrated in synthesizing isoquinoline derived natural products. This strategy provides an efficient, mild and inexpensive method for acylation of heteroarenes.
Graphical abstractDownload high-res image (163KB)Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yogesh Siddaraju, Kandikere Ramaiah Prabhu,