Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5213893 | Tetrahedron | 2015 | 5 Pages |
Abstract
An efficient approach for the enantioselective synthesis of the 1,4-benzodioxane F17807 drug is reported. The developed route relied on two key steps, namely SNAr and Mitsunobu reactions, which permitted a straightforward access to the title compound with full preservation of the enantiomeric excess throughout the synthetic sequence.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Julien Alliot, Edmond Gravel, David-Alexandre Buisson, Laurent Larquetoux, Marc Nicolas, Eric Doris,