| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5213894 | Tetrahedron | 2015 | 8 Pages |
Abstract
An efficient, mild, cost effective and practical method is presented for generation of esters (RCO2Râ²) from acids (RCO2H)/ 2-oxoacids (RCOCO2H)/ 2-oxoaldehydes (RCOCHO)/ 2-oxoesters (RCOCO2Râ³) and alcohols by using oxone as catalyst. In addition to deciphering the scope of our process, we propose a mechanism for esterification through a common intermediate IV. Reaction with 2-oxoacids and 2-oxoaldehydes proceed with initial CO-C cleavage followed by oxone mediated esterification with alcohols. In addition, reaction with 2-oxoesters proceeds through CO-CO bond cleavage and trans-esterification.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anil K. Padala, Varma Saikam, Asif Ali, Qazi Naveed Ahmed,